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Trainz Simulator 2010 Romania Torent Description
Download Trainz Simulator 2010 Romania Torent Overview- Trainz Simulator 10 comes with a new engine integrated into the game – the Trainz 10 engine. This new Engine makes the railroad simulation experience much more realistic. New train and control components.The article is devoted to the problem of an effective treatment of the peripheral nerve paralysis. The dynamics of the regeneration process after the neurotrophic factors action is considered, some neuroprotective strategy is analyzed, the attention is paid to the implementation of the therapeutic strategies and possibilities of future aspects of the neurorehabilitation using the neurophysiological approach.
Material and methods {#S0001}
====================
Nerve transection models, the axonotmesis and the neurotmesis, are used to simulate the peripheral nerve paralysis. Their modeling is accompanied by the recording of the action potentials (AP) by means of the intracellular microelectrodes. Such models permit the simulation of a real nerve wound, focusing attention on the regenerative activity of the axons and on the endoneurial microenvironment. The main methods of the work are described below.
Animal models {#S20002}
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The experiments were performed on Wistar rats of both sexes (250–300 g) with the approval of the National Academy of Sciences of Ukraine. The surgery was performed on the distal part of the tail on the right side of the rat. Surgical anesthesia was performed using an intraperitoneal injection of the anesthetics-ketamine (100 mg/kg) and xylazine (10 mg/kg). After the surgery, the wound was sutured. The right distal tibia and the foot were amputated with the help of an orthopedic circular saw. After the operation, the animals were put on the heating pad. The first results of the experiment were recorded after 7 days.
Behavioral testing {#S20003}
——————
The mechanical allodynia was estimated by means of the aversive response to the application of mechanical stimulation (paw pressure). An electrical stimulator (0
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